CYSTINE/GLUTAMATE ANTIPORTER XCT DEFICIENCY REDUCES METASTASIS WITHOUT IMPAIRING IMMUNE SYSTEM FUNCTION IN BREAST CANCER MOUSE MODELS

Cystine/glutamate antiporter xCT deficiency reduces metastasis without impairing immune system function in breast cancer mouse models

Abstract Background The upregulation of antioxidant mechanisms is a common occurrence in cancer cells, as they strive to maintain balanced redox state and prevent oxidative damage.This includes the upregulation of the cystine/glutamate antiporter xCT, which plays a crucial role in protecting cancer cells Occupational from oxidative stress.Consequen

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Graph Representation Learning and Its Applications: A Survey

Graphs are data structures that effectively represent relational data in the real world.Graph Bedding representation learning is a significant task since it could facilitate various downstream tasks, such as node classification, link prediction, etc.Graph representation learning aims to map graph entities to low-dimensional vectors while preserving

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Identification and Functional Characterization of a Microtubule-Associated Protein, GhCLASP2, From Upland Cotton (Gossypium hirsutum L.)

Cytoplasmic linker-associated proteins (CLASPs) are microtubule-associated proteins (MAPs) involved in regulation of dynamics of microtubules (MTs) that play an important role in plant growth and development.In this Faux Animal Head study, we identified cotton CLASP genes and investigated the function of GhCLASP2.GhCLASP2 was mainly expressed in st

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